RESOLUTION NO. _____________

BOARD OF SUPERVISORS, COUNTY OF SAN MATEO, STATE OF CALIFORNIA

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RESOLUTION 1)ACCEPTING A GRANT FROM THE SMITHKLINE BEECHAM CORPORATION DBA GLAXOSMITHKLINE (GSK) IN AN AMOUNT NOT TO EXCEED $226,861 TO CONDUCT A CLINICAL TRIAL EVALUATING THE EFFICACY AND SAFETY OF GW873140 IN HIV-1 INFECTED PATIENTS, AND 2) AUTHORIZING THE EXECUTION OF AN AGREEMENT WITH SMITHKLINE BEECHAM CORPORATION, DBA GLAXOSMITHKLINE (GSK), TO CONDUCT THE CLINICAL TRIAL FOR THE TERM MAY 23, 2005 UNTIL THE TRIAL IS COMPLETED IN AN AMOUNT NOT TO EXCEED $226,861

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RESOLVED, by the Board of Supervisors of the County of San Mateo, State of California, that

WHEREAS, the Clinical Trials and Research Unit of the San Mateo County Health Center was established by the Health Services Agency in 2000 in order to provide a mechanism and infrastructure for the conduct of clinical treatment trials and medical or psychosocial research projects for the benefit of the residents of San Mateo County; and

WHEREAS, a preliminary assessment by the Unit staff identified HIV/AIDS as a problem affecting many of the County’s patients. The Clinical Trials and Research Unit discovered that patients are not responding to the current drug treatments. This trial will evaluate patient’s response to this new drug treatment; and

WHEREAS, there has been presented to this Board of Supervisors for its consideration and acceptance an Award, reference to which is hereby made for further particulars, whereby SmithKline Beecham Corporation Dba GlaxoSmithKline (GSK) will allocate funds in an amount not to exceed of $226,861 for the provision of a research study for persons with HIV/AIDS.

WHEREAS, there has been presented to this Board of Supervisors for its consideration and acceptance a Agreement with SmithKline Beecham Corporation, dba GlaxoSmithKline (GSK), to conduct a clinical trial evaluating the efficacy and safety of GW83140 in HIV-1 infected patients, for the term May 23, 2005 until the trial is completed, in an amount not to exceed $226,861; and

WHEREAS, this Board has been presented with the Award and the Agreement and desires to accept the award and enter into the Agreement.

NOW, THEREFORE, IT IS HEREBY RESOLVED that the Board of Supervisors be, and is hereby authorized and directed to accept said Award and execute said Agreement for and on behalf of the County of San Mateo, and the Clerk of this Board shall attest the President's signatures thereto.

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